Analog Devices has created the AD8250ARMZ, an innovative built precision instrumentation amplifier with configurable gain. This device is recognized for its high performance and versatile application utility. The following considerations ought to be made while creating an application circuit for the AD8250ARMZ:

1. Power Supply: The AD8250ARMZ operates between a wide supply voltage range of ±4.5V to ±18V. Bypass capacitors should be connected close to the supply pins to filter supply noise and to provide instantaneous charge needed for transient conditions.

2. Gain Configuration: The gain of AD8250ARMZ can be set to 1, 2, 5 or 10 V/V by the two digital control inputs G0 and G1. The right gain should be selected depending on the application needs.

3. Input Biasing: This device can handle a large common-mode voltage range, but it is essential to consider that the input common-mode voltage along with the signal amplitude must be within the power supply voltage.

4. Output Considerations: The AD8250ARMZ has a wide output swing which approaches the supply voltage. The next circuitry must be carefully checked to make sure it can withstand these voltage levels.

5. Protection Circuitry: Protection circuits can be added to the inputs and outputs of the device to ensure the device is not exposed to any voltages or currents beyond its absolute maximum ratings.

6. Board Layout: The printed circuit board (PCB) layout can significantly affect the performance of precision amplifiers like AD8250ARMZ. A well-designed PCB layout minimizes electromagnetic interference (EMI), ground loops, and crosstalk between traces.

While these are some essential elements to consider, a detailed application circuit design requires careful study of the AD8250ARMZ's data sheet and any associated application notes. The details of the planned application will have a significant impact on the circuit configuration.